Samuel Stephens, Ph.D.
Title/Position
Associate Professor of Internal Medicine
Associate Professor of Anatomy and Cell Biology
My scientific training in cell biology, metabolism, and endocrine physiology have shaped my long-standing interest in understanding how cells adapt to nutrient and stress signals. I received my B.S. in Biochemistry and Molecular Biology from the University of Georgia—Go Dawgs! I then worked as a research assistant at the Complex Carbohydrate Research Center at UGA, studying plant and bacterial cell wall structures. I went on to earn my Ph.D. in Cell Biology at Duke University in the lab of Dr. Christopher Nicchitta, where I studied ER stress regulation of protein synthesis. I completed my postdoctoral training with Dr. Christopher Newgard at the Duke Molecular Physiology Institute, where I studied pancreatic islet β-cell function. Collectively, these experiences led me to build a research program aimed at uncovering fundamental mechanisms that contribute to β-cell dysfunction in major forms of diabetes.
My laboratory brings together expertise in secretory protein trafficking, organelle biology, and β-cell signaling to understand how metabolic and inflammatory stresses reprogram the β-cell secretory pathway. A defining feature of our work is the use of sophisticated imaging platforms to visualize organelle dynamics in real time, allowing us to directly link molecular mechanisms to β-cell health and disease. I am deeply committed to hands-on mentoring and to fostering a collaborative, supportive, and rigorous training environment, with the goal of helping trainees grow into independent, confident scientists who value curiosity, integrity, and excellence.
My laboratory brings together expertise in secretory protein trafficking, organelle biology, and β-cell signaling to understand how metabolic and inflammatory stresses reprogram the β-cell secretory pathway. A defining feature of our work is the use of sophisticated imaging platforms to visualize organelle dynamics in real time, allowing us to directly link molecular mechanisms to β-cell health and disease. I am deeply committed to hands-on mentoring and to fostering a collaborative, supportive, and rigorous training environment, with the goal of helping trainees grow into independent, confident scientists who value curiosity, integrity, and excellence.
Lab Members
Sandra Blom, Ph.D.
Title/Position
Post-doctoral fellow
Ph.D. Molecular Medicine
Dalal El-Ladiki, M.D.
Title/Position
Post-doctoral fellow
Amira Zaher, Ph.D.
Title/Position
Post-doctoral fellow
Joy James
Title/Position
Graduate student
Cell and Developmental Biology Graduate Program
Palin Narsian
Title/Position
Undergraduate research assistant
Major: Biomedical Engineering
Alex Nugent
Title/Position
Undergraduate research assistant
Major: Biomedical Engineering
Aubrey Olson
Title/Position
Undergraduate research assistant
Major: Health and Human Physiology
Alumni
Casey Bauchle
Title/Position
Research Associate
Shelby Bearrows
Title/Position
Research Associate
McKenzie Becker
Title/Position
Undergraduate research assistant
Major: Chemistry
Cierra Boyer, Ph.D.
Title/Position
Graduate student
Ph.D. Pharmacology
Weston Elison
Title/Position
Summer Research Fellow
Ashleigh Machado
Title/Position
Undergraduate research assistant
Major: Biochemistry
Marshall Moyer, M.D.
Title/Position
Medical research fellow
Taryn O'Brien, M.S.
Title/Position
M.S. Clinical Anatomy
Kristen Rohli, Ph.D.
Title/Position
Graduate student
Ph.D. Interdisciplinary Program in Genetics
Nicole Stubbe
Title/Position
Undergraduate research assistant
Major: Biomedical Engineering
Svetha Swaminathan
Title/Position
Research Associate
Jenna Zimmerman
Title/Position
Summer medical research fellow