SamStephens

Samuel Stephens, Ph.D.

Title/Position
Associate Professor of Internal Medicine
Associate Professor of Anatomy and Cell Biology
My scientific training in cell biology, metabolism, and endocrine physiology have shaped my long-standing interest in understanding how cells adapt to nutrient and stress signals. I received my B.S. in Biochemistry and Molecular Biology from the University of Georgia—Go Dawgs! I then worked as a research assistant at the Complex Carbohydrate Research Center at UGA, studying plant and bacterial cell wall structures. I went on to earn my Ph.D. in Cell Biology at Duke University in the lab of Dr. Christopher Nicchitta, where I studied ER stress regulation of protein synthesis. I completed my postdoctoral training with Dr. Christopher Newgard at the Duke Molecular Physiology Institute, where I studied pancreatic islet β-cell function. Collectively, these experiences led me to build a research program aimed at uncovering fundamental mechanisms that contribute to β-cell dysfunction in major forms of diabetes.

My laboratory brings together expertise in secretory protein trafficking, organelle biology, and β-cell signaling to understand how metabolic and inflammatory stresses reprogram the β-cell secretory pathway. A defining feature of our work is the use of sophisticated imaging platforms to visualize organelle dynamics in real time, allowing us to directly link molecular mechanisms to β-cell health and disease. I am deeply committed to hands-on mentoring and to fostering a collaborative, supportive, and rigorous training environment, with the goal of helping trainees grow into independent, confident scientists who value curiosity, integrity, and excellence.

Lab Members

Sandra

Sandra Blom, Ph.D.

Title/Position
Post-doctoral fellow
Ph.D. Molecular Medicine
Herky

Dalal El-Ladiki, M.D.

Title/Position
Post-doctoral fellow
AmiraZaher

Amira Zaher, Ph.D.

Title/Position
Post-doctoral fellow
Joy

Joy James

Title/Position
Graduate student
Cell and Developmental Biology Graduate Program
Palin

Palin Narsian

Title/Position
Undergraduate research assistant
Major: Biomedical Engineering
Alex

Alex Nugent

Title/Position
Undergraduate research assistant
Major: Biomedical Engineering
Aubrey

Aubrey Olson

Title/Position
Undergraduate research assistant
Major: Health and Human Physiology

Alumni

Casey

Casey Bauchle

Title/Position
Research Associate
Shelby

Shelby Bearrows

Title/Position
Research Associate
McKenzie

McKenzie Becker

Title/Position
Undergraduate research assistant
Major: Chemistry
Cierra Boyer photo

Cierra Boyer, Ph.D.

Title/Position
Graduate student
Ph.D. Pharmacology
Weston

Weston Elison

Title/Position
Summer Research Fellow
Ashleigh Machado photo

Ashleigh Machado

Title/Position
Undergraduate research assistant
Major: Biochemistry
Marshall

Marshall Moyer, M.D.

Title/Position
Medical research fellow
Taryn

Taryn O'Brien, M.S.

Title/Position
M.S. Clinical Anatomy
Kristen Rohli photo

Kristen Rohli, Ph.D.

Title/Position
Graduate student
Ph.D. Interdisciplinary Program in Genetics
nicole

Nicole Stubbe

Title/Position
Undergraduate research assistant
Major: Biomedical Engineering
Herky

Svetha Swaminathan

Title/Position
Research Associate
Jenna

Jenna Zimmerman

Title/Position
Summer medical research fellow